Tweety's S.O.S. (1951)

Sylvester Cat stows away aboard a seagoing passenger liner to try and catch Tweety Bird, who is guarded by his mistress, Granny. Sylvester becomes seasick and runs to the sickbay for a remedy. Tweety mixes nitro into the medicine before Sylvester drinks it. When Granny hits Sylvester with her broom, he is blown sky-high.